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THB that expanding access to human GET is more beneficial than harmful

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发表于 4 天前 | 显示全部楼层 |阅读模式
本帖最后由 Yolanda 于 5-7-2025 20:56 编辑

这个标题是NHSDLC在本赛季Public Forum辩论中的辩题,GET是指Gene Editing Technology,也就是基因编辑技术基因编辑技术
百度是这样说的:
基因编辑技术是指通过基因编辑技术对生物体基因组特定目标进行修饰的过程。高效而精准地实现基因插入、缺失或替换,从而改变其遗传信息和表现型特征。
Bing是这样说的:
Gene editing, also known as genome editing, refers to the ability to make highly specific changes in the DNA sequence of a living organism, essentially customizing its genetic makeup. Gene editing is performed using enzymes, particularly nucleases that have been engineered to target a specific DNA sequence, where they introduce cuts into the DNA strands, enabling the removal of existing DNA and the insertion of replacement DNA.
我个人比较喜欢把它理解为这样:





基因编辑到底多贵?
A single injection of Hemgenix for adult patients with haemophilia B costs USD 3.5 million. Hemophilia B, cost about $20 million over the course of their life, $300,000 to $500,000 per year, Stacy E. Croteau, February 1, 2020
这是我在必应搜到的资料,简单讲就是把现有的治疗方案和基因编辑放到一起做比较,看看哪个更贵。这里我举了血友病的例子,一针基因编辑治疗要350万美元,也就是2528,8550人民币。而现有治疗方案一年需要花费30万到50万美元,终生花费2000万美元,1,4450,6000人民币(也是上亿了),我在自己辩论的时候就听到很多人说基因编辑太贵了,但是(The Average Cost Of A Single-Dose Gene Therapy Treatment Ranges Between $500,000 To $3.5 Million Bao Tran, Patent Attorney on Mar 29, 2025 )如果人家没有上亿的付不起,那是怎么承担得起一亿多的终身治疗?更何况,基因编辑会相对合算,不仅更便宜,而且病人还没那么痛苦,就不用终生受难。(就算是说普通治疗可能会便宜,但是一辈子都在痛苦中度过,真的值吗?)
基因编辑安全吗?
必应资料:
The Alliance for Regenerative Medicine (ARM), the leading international advocacy organization championing the benefits of engineered cell therapies and genetic medicines, today announced new analysis showing that durable cell and gene therapies have clinical success rates between two and three times higher than other types of treatments.
所以说,基因编辑是相对而言很安全的,没有什么问题
(附件可供参考,是我辩论的论点,应该是文件太大无法上传,所以只能截图上传照片)

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